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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

康涅狄格州斯托宁顿(STONINGTON, CONN.)
2016年中国迅猛发展的网红经济可能会达到87亿美元

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

China must walk a narrow line at a time when its outgoing leadership is reluctant to take any far-sighted decisions.
nutrition

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
From the themed collection: 石材加工企业整治新标准出炉
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

10.邮差

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

现在iPhone又夺回声势,对Apple Watch的期待也在升温,库克似乎重新赢得了苹果员工的信任。分析师表示,这一点从他在今年产品发布会上的表现就可以看出来。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

It is the first time since 2001 that an athlete other than Mayweather Jnr or golfer Tiger Woods topped the earning league.
Next year, the mayor’s affordable housing plan, which calls for building or preserving 200,000 units of affordable housing over the next decade, will begin to take shape. It hinges on a policy that requires developers to build affordable housing in exchange for being allowed to construct taller and denser buildings in neighborhoods rezoned by the city. Developers and housing advocates alike are waiting to see what it will look like once the administration adds muscle and flesh to the bones of the proposal.
《寻梦环游记》
“我试图做到的是继承他的衣钵,写一本典型的伊恩·弗莱明式的007小说。”

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

The history of James Bond theme songs isn't quite as long as some might suspect, however. The first two films in the series – Dr. No and From Russia With Love – didn't have opening songs, they had orchestral arrangements. Dr. No even segued into a weird rendition of "Three Blind Mice." Later on, On Her Majesty's Secret Service gave the opening number amiss and snuck its theme song into the middle and end of the movie.
The scientists’ analysis comes only a month after nearly 200 governments struck a new climate agreement in Paris that aims to stop global temperatures from rising more than 2C from pre-industrial levels, and ideally limit warming to 1.5C.
除了跳舞,玛蒂还唱歌和表演,她已经出演了电视剧《美女上错身》(Drop Dead Diva)和《奥斯汀与艾丽》(Austin & Ally)。
本届电影节最大新闻与电影无关,而是关于鞋子。据《银幕日报》报道,上周二(5月19日),数名女性在去参加托德?海因斯(Todd Haynes)执导的《卡罗尔》(Carol)首映红毯时,因穿着装饰有莱茵石的平底鞋,而被工作人员以不符合规定为由拒之门外。报道一出,社交媒体上义愤填膺。戛纳新闻办公室仓促应对,称该报道断章取义:“这么多年来,电影节的规则都没有变过(参加电影节放映会,男士着无尾半正式晚礼服,女士穿正式礼服。)而对女性高跟鞋的跟高没有特定的要求,同样对男性的亦无特殊要求。”因此,为了确保遵守规则,男女主持会被提醒记住这些规则。好了,这下清楚了,媒体放映场没有任何着装要求:着装邋遢的记者们可穿着人字拖与运动鞋随意踏上皇宫广场(Palais)的阶梯。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

然而抓捕犯罪团伙十分困难。非法肉类食品常常混藏在水果蔬菜等农产品之间,卡车司机收到好处费后也拒绝承认对此事知情。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

INDOORS: This house was completed around 1848 and last updated in 2008. The front door has a transom and sidelights of red glass etched with a leaf motif. The first floor has a large living room with crown molding and two fireplaces, one of which warms the formal dining area. Off the living room is a family room with raised wall paneling, a wet bar and another dining area. French doors open to a slate patio. Several rooms have views of Little Narragansett Bay.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

1、拖延
2.Artificial Eyes

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

That cold was drawn into the interior of the country by a loop in a current called the jet stream that allowed Arctic air to spill southward. But an offsetting kink allowed unusually warm tropical air to settle over the West, large parts of Alaska and much of the Arctic.
立场:支持移民改革

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

凯洛格/香港科大EMBA项目的优势在于学员的素质。
STEP 6: FIND A WATSON

Graphical abstract: Diagnostic technologies for COVID-19: a review
From the themed collection: 深圳深入推进住宅区垃圾分类
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

[k?n'denst]
Charli XCX, 'Number 1 Angel'
Emily Ratajkowski managed to steal the show, opting for a seriously saucy twist on the classic ballgown. Opting for a semi-sheer lacey black number, the We Are Your Friends actress ensured her world-famous figure was on display.
一位新浪微博网友写道:“不敢相信这么多医生都在论文中造假。病人还能相信他们可以帮人治病吗?”

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Wang Dengfeng, director of the Physical Education, Health and Art Department under the Ministry of Education (MOE) and Vice Chairman of the China Football Association, was quoted as saying that football experts are designing curriculums for more than 360 training programs in primary and secondary schools.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

但他认为自己任教的经历非常宝贵,可以让他很快适应新的职业阶段。
当小李子上台领取奖杯时,制片人哈维·韦恩斯坦兴奋地拍拍他的背,全场观众起立为他喝彩。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

draft

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Song “Family”(Tan Jing)

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
From the themed collection: 南京官方租房平台挂牌房源逾万
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

US president Donald Trump’s zero-sum, Art-of-the-Deal approach to negotiation will give comfort to old-fashioned incumbents. I am hoping 2018 will provide an opportunity for positive, problem-solving new leaders to emerge. But change could stall if business chiefs, disheartened by the poor quality of political leadership, turn inwards instead.
根据康奈尔大学、英士国际商学院和世界知识产权组织联合发布的这一份报告,这使得中国成为中等收入经济体中该指标的领先者,紧随其后的是已经超过巴西的印度。
"How many patients do Chinese doctors see a day? It can be more than 50," he told China Daily. "How can we have the time and energy to do research or publish papers?"
Chicago-based rival AT Kearney is also preparing for a change at the top, with a vote to replace Johan Aurik, who has already served the maximum two terms as managing partner, due to take place in the first quarter of 2018. His replacement will be expected to focus on how to pull AT Kearney out of the ranks of mid-sized players.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

大卫评价说:“这唱的太棒了,无可挑剔,简直完美。”
一位伦敦软件神童的“硅谷梦”成真,雅虎(Yahoo)斥资近3000万美元收购了他制作的新闻应用。
The details of her character are being kept under wraps.
由于最新一部007系列小说给詹姆斯·邦德(James Bond)进行了政治正确的大改造,能言善道、烟不离口、大男子主义的邦德形象可能将成为过去式。
I mean, is it worth to be a No. 8 seed with Serge Ibaka and Jeff Green leading the way? Maybe it is. This all just seems awfully backwards.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

特里萨?梅(Theresa May)依然面临着党内阻力。自由民主党(Liberal Democrats)的智者兼领导人文斯?凯布尔(Vince Cable)依然认为脱欧可能不会真的发生。
约翰奥瑟兹(John Authers)

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

Exports to the EU, Japan and Hong Kong — which serves as a transit point for exports to many other parts of the world — fell by 4.1 per cent, 9.5 per cent and 12.2 per cent respectively.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

当年的荷兰金融市场固然没有今天的任何科技,但他们的很多做法都和今天的交易员一样。投资者们买入证券,有时会用买入的股票质押获得贷款。用今天的话说,他们基于保证金买入股票。贷款机构为了自身安全,会要求一个超出贷款金额一定百分比的“折幅”,质押现金或证券。如果证券价格下跌超过一定幅度,贷款机构会要求投资者交出更多资金,与“折幅”保持一致。如果投资者拿不出追加保证金,贷款机构有权将证券平仓,收回贷款额。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

Plante Moran
-
《傲骨贤妻》(The Good Wife):艾丽西娅(Alicia)的秘密暧昧对象威尔(Will,乔希·查尔斯[Josh Charles]饰)在第五季末死去,CBS频道的这部性感法庭剧似乎要完蛋了,但是第六季却似乎充满了疯狂的能量——艾丽西娅初露头角的政治竞选、新旧公司的权力之争、合伙人卡里(Cary)的棘手法律事务。艾丽西娅不再那么完美,《傲骨贤妻》因此更好看了。
我去年就说过、今年要再强调的一点是:唯一比预测未来更不招人待见的事情就是公开自己的预言。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

About 40 per cent of entrepreneurs did not seek any help when securing finance. Half of these raised equity purely from their own savings and/or family and friends compared with only 40 per cent of those who sought help from the school or alumni network.
借助于Artnet等公布拍卖结果的数据库,如今购买艺术品的富豪非常清楚要想在早期绘画大师的作品上获利非常困难。
8. Taxi driver
n. 没精打采的样子,耷拉,笨人 v. 没精打采地站,坐

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

不过,在财经领域,激烈竞争也是不可避免的。毕业生进入职场后应从基础工作开始,一步步提升综合能力,保持自身竞争力。
But there's even more to be excited about: Magic Johnson is a well-connected and well-respected Hall of Famer who seems smart enough to delegate, new GM Rob Pelinka is a proven deal-maker with extensive ties throughout the league,

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

小贝现身纽约时装周 为凯特选嫁衣?
He and his girlfriend wrote to each other when he was studying science, he said.They did eventually marry and have four children.
A report on entrepreneurship among Chinese college students published by Renmin University of China revealed an inverse proportion between the level of students' academic degrees and their intentions to start their own businesses.
价格:197.5万元(约合人民币1264万元)
但是,贝克?麦坚时律所并购业务主席迈克尔?德佛朗哥(Michael DeFranco)对中国企业在发达经济体投资表示赞赏。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

WHAT: A riverfront contemporary with three bedrooms and three and a half bathrooms
It organized two large-scale inspections last year, involving more than 5,300 batches of imported consumer goods, such as air purifiers, car brake blocks, household electrical appliances and clothes, with more than 1,500 found to be substandard, Han said.
译者:清远

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
From the themed collection: 43个重大项目进展缓慢或长期停工
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

Obama watched the returns on television at his Chicago home. Senior campaign strategist David Axelrod said via email that he was feeling "great."
The announcement comes from the British Fashion Council (BFC), who surveyed designers ahead of the shows and found none of the 80 designers in the September line-up would be using fur.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

over $50,000 category, pickups and SUVs distributed through non-premium dealers outsell German luxury brands.
为什么我如此有信心东亚不会爆发战争,无论在东中国海还是南中国海?答案很简单,因为我了解推动亚洲变化的力量。虽然许多亚洲邻国会发出愤怒的民族主义声明(他们必须这样做来应对普遍的民族主义情绪),但他们的行动是谨慎和务实的。
8月11日

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

今年发展的主要预期目标是:
Fiat will seek to renegotiate the terms of its investment in Chrysler.
10.Supersensitive Electronic Skin

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
From the themed collection: LED照明行业新三板上市热
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

总体来说,直播授课和录制内容均获得8.8分的高分(满分10分),在线互动和团队合作的评分略低。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

That creates an identity vacuum to be filled.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

A teenage student in Southwest China's Chongqing Municipality has been sentenced to one year in jail after trying to poison fellow students for being too noisy in class, local media reported last Wednesday.
contribution

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

BuzzFeed News defined “fake news” as news that was verifiably “100 percent false” and drawn from a list of 96 websites purposely created to disseminate false information.
That Apple could launch a 2,000 yuan ($330) iPhone mini and be competitive with flagship products from Lenovo, Huawei, ZTE and Coolpad.
在上榜的90所欧洲商学院中,法国的欧洲工商管理学院(Insead)在全日制MBA课程和EMBA课程方面居首,瑞士圣加伦大学(St Gallen)的管理硕士课程排名第一。西班牙Iese商学院(Iese Business School)和瑞士洛桑国际管理发展学院(IMD)分别在定制和开放注册高管教育课程上夺魁。
Tesla:In an effort to blunt criticism about slow refueling times for battery-powered cars, Tesla TSLA -1.54% starts to roll out of a network of battery-swap stations. CEO Elon Musk must hope he can outdo Shai Agassi’s Better Place, which tried to build a whole company around battery-swaps before going bankrupt in 2013.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

Baby Driver recently placed on the National Board of Review’s Top 10 list. The film holds a 93% on Rotten Tomatoes and took in over $100 million dollars at the box office.
['k?nsnis]

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

manifest显示,证明+o表名词,“人,物或状态”→宣言,声明
Teach First自成立以来将5000名毕业生送入学校任教,与低收入地区的逾100万学生合作,帮助提高了教学质量,尤其是伦敦地区的教学质量。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

vt. 包含,容纳,克制,抑制

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

Jack Ma, founder and executive chairman of e-commerce giant Alibaba Group topped the ranking of China's richest IT people for the third consecutive year.
9. Smart wine bottle
The magazine also notes that he gave $66 million to his presidential campaign and paid $25 million to settle a lawsuit related to Trump University.
Tracey and Viv Williams, a British couple, dressed as the green cartoon ogres from Shrek at their wedding held recently. Tracy, 33, made a lovely Princess Fion

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

桑尼伯恩说他不仅对特朗普的错误决定和无知时期感到失望,同时也因为总统对8月在弗吉尼亚州夏洛茨维尔举行的白人种族主义集会上反抗者被杀害后做出的回应感到失望——这也更加坚定了桑尼伯恩竞选州长的决心。
Brazil lost that 1950 final, 2-1, to Uruguay, a historic humiliation that still stings Brazilian fans today. Belmonte, 85, hopes he'll get to see his country regain its honor. "I hope Brazil will be able to win this time," he said. "This is our revenge. I want to go see our revenge."

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

The drama and the original game have a large fan base and enjoy great popularity in China, and even elsewhere in Asia.
他表示,目前腾讯旗下的游戏和直播应用不需要实名注册,不过腾讯公司正在考虑建立一个平台,以方便家长监护孩子的行为。
与比利时接壤的法国已经有大量志愿者出国加入伊斯兰国圣战组织,这个组织占领了伊拉克和叙利亚的大片区域。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

Company: Eventbrite
不过,这种风潮好像不是在表达如今的女人想穿什么,而是在逃避,认为最安全的着装方式是回归过去,我认为这种想法是错误的。
And the public chose Callabro to be crowned this year's winner, where they will take home a £250,000 cash prize and a spot at this year's Royal Variety Performance.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

Gideon Rachman
The rest of them, he goes over quickly:

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
From the themed collection: 楼市冰火两重天 下一步何去何从
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

8. Trang Islands, Thailand-The islands of Trang, a sleepy province in southeast Thailand, have remained under the radar. Wooden longtail boats can be rented to travel between the islands—and to see the endangered dugongs.
purchase
它们大多来自50个不同的行业,包括食品和饮料、汽车和汽车零部件、媒体、零售、能源和互联网。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

v. 调查,检查,测量,勘定,纵览,环视
我判断摆烂不是看言论而是看球队动作的。所以,即使球队说他们没有摆烂,但是签了一大批落选的自由球员,同时报告明星球员伤病缠身,这时候你就知道,他们是在摆烂了。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

扎克伯格还协助成立了一个名为FWD.us的游说团体,旨在推动美国的移民和教育改革。
就目前而言,虽然偶尔出现一些高价交易(比如大新金融中心、以21亿港元售出的太平山顶豪宅),但整个行业弥漫着广泛的悲观情绪。世邦魏理仕数据显示,今年第一季度房地产业最活跃的部分是写字楼,但交易总量也不过8笔。
Joakim Noah, meanwhile, proved to be so untradeable that he couldn't even generate a rumor.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
From the themed collection: 愿奋斗者们住有所居,心有所属
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

贝莱德(BlackRock)的iShares亚太区主管陈蕙兰(Susan Chan)表示,ETF更受该地区机构投资者的欢迎。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

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Welcome as they were, surging sales weren't the biggest news of the year. Detroit celebrated when General Motors (GM, Fortune 500) made Mary Barra the auto industry's first female CEO, then held its breath while Ford (F, Fortune 500) CEO Alan Mulally dithered over a move to Seattle and Microsoft. The old Big Three, complaining about straining available production capacity, made plans to expand and hire. Tesla(TSLA) fired up electric car sales and refused to play by industry's rules, while Google(GOOG, Fortune 500) pioneered a car that drives itself.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Figures released by the International Society of Aesthetic Plastic Surgery (ISAPS), suggest that when population is taken into account, South Korea is now the world's largest market for cosmetic procedures.
让爱情多姿多彩:荷兰培育出彩虹玫瑰(图)

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

1.Under no circumstances should you ask your taxi driver how excited he is about having the Olympics in London this summer. It's not that he will be reluctant or embarrassed to offer a personal opinion on the matter. That is not the problem at all.
除了作为微信核心的私聊和群卿功能之外,用户还可以通过“漂流瓶”功能寻找新的好友,具体方法是录制一段信息装在虚拟的“瓶子”里扔出去,等陌生人捡起来回复。“查看附近的人”功能与一些手机交友应用相似,用户通过它可以浏览附近其他用户的资料。另外还有一个名叫“朋友圈”的功能,用户通过它可以将相册公开分享给好友群,跟照片分享应用Instagram很像。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

4. Add Color
《大唐荣耀》

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

The country's film output ranks third in the global market and is expected to exceed 700 by the end of 2016. Sales of film rights to online video sites raked in 4 billion yuan (560 million U.S. dollars) in the same period.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

I know many of you met your former spouse at the company. But the thing is, for every one of you, there are five people it doesn't work out as well for. And your office romance can and will be held against you.
5. 范冰冰 1700万美元
China will "fasten the seat belt" and prevent any "acute outburst" of financial risks on the track for maintaining medium-high growth speed.
5. Geopolitical flashpoints.In the not too distant past, a small supply disruption would send oil prices skyward. In early 2014, for example, violence in Libya blocked oil exports, contributing to a rise in oil prices. In Iraq, ISIS overran parts of the country and oil prices shot up on fears of supply outages. But since then, geopolitical flashpoints have had much less of an effect on the price of crude. During the last few weeks of 2014, violence flared up again in Libya. But after a brief increase in prices, the markets shrugged off the event. Nevertheless, history has demonstrated time and again that geopolitical crises are some of the most powerful short-term movers of oil prices.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

"He promised when he took office that he would have a Cabinet that was 50 percent women, and then he did it," Maddow said. "Would you make that same pledge?"

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

沙泽勒编导的音乐片《爱乐之城》是当晚的得奖热门,所获14项提名平了奥斯卡史上的纪录。沙泽勒获得最佳导演奖。而埃玛?斯通(Emma Stone)凭借她在这部由狮门娱乐(Lionsgate)制作的影片中的表演,赢得了最佳女主角奖。此外,《爱乐之城》还获得了最佳配乐和最佳原创歌曲奖。
根据中国海关的数据,今年头十个月,中国对美国出口同比增长5.2%,对东盟(Asean)国家出口同比增长3.7%。
欢迎来到英国,不过在我开始介绍之前请先接受我们的道歉。你们在入境检查时等了4个小时的噩梦本不应该是英国轻视外国人的象征。这只反映了英国在一项如此重要的赛事来临时对旅游基础建设的投入严重不足。换句话说,是英国政府怠慢了你们。别不开心,政府对我们也不咋地。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

在这个越来越为人类所主宰的星球上,我们仍然可以从其他物种身上学习到很多东西。格陵兰鲨鱼可存活400年,是世界上最长寿的脊椎动物,这一发现让人类重新审视自己忙碌的人生。
4.Candice Swanepoel

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
From the themed collection: 标准是智能家居普及的最大阻碍
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

以下是根据官方数据(所有收入均按市场汇率折合成了美元)得出的世界主要国家领导人收入排行。
但是,当《老友记》第二季浓墨重彩地展现卡罗尔和苏珊的同性恋婚礼时,这个剧集就朝着人人平等的方向迈出了一大步。幕后,执行制片人玛塔·考夫曼说:"国家广播公司预计会接到成千上万的投诉电话和邮件"。然而在这部剧集上映之后,收到的恶意信件却是寥寥无几。原来,大家根本就不在乎。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
From the themed collection: 广东清远住建局:备案价不得上调
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

Coco

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

According to the report, people living in first-tier cities such as Beijing, Shanghai, Guangzhou and Shenzhen suffer much higher economic pressure, while fourth-tier and smaller cities offer fewer job opportunities and connection plays an important role in every aspect of life there.
智联招聘最近的一份调查报告显示,在参与调查的2016届应届毕业生中,毕业后选择创业的比例为仅仅只有3.1%,而2015年的比例是6.3%。
据中国科协21日发表的声明称,在会谈中,王春法对安诺杰表示,中国正在进行科技管理体制改革,此类问题将有所减少。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

[k?'m?:l]
他说:“比如说,如果他们拖延从韩国进口的海关流程并采取对韩国商品的其他报复举措,韩国政府对此将无能为力。”
顺便说一句,伦敦的自行车租赁制度再简单不过了:走到任何一个租车点,刷卡付费就可以带走一辆自行车。当你使用完毕时,把车丢在附近的河里就行。这些自行车都是一次性的!
The reason is twofold: For one, logistically, there are simply too many opportunities to get caught job searching. Résumé copies will be found. Computer servers will be checked. Co-workers will notice when you're clearly elsewhere, either literally for interviews or emotionally (more on that later)。

Graphical abstract: Length-scale dependence of protein hydration-shell density
From the themed collection: 加快陶瓷“制造”向“智造”转变
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

夏洛特·艾玛·艾奇逊《1号天使》
本默切重振公司士气的艰苦努力将取得回报。美国“薪酬沙皇”将对他网开一面。而且各个市场的持续回暖将令公司有机会偿还一大笔美国纳税人的救助资金。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

我以前曾有过一款安卓手机(尽管2009年以来我一直用的是MacBook笔记本电脑,这种搭配挺诡异的,我知道)。自从今年夏天换了iPhone以后,我马上意识到了iPhone“提醒”的力量。每次有提醒事项时,iPhone就会振动起来,然后显示一个弹出窗口,你可以暂停它,或者把它标记为已完成。另外你还可以设置重复提醒,用来提醒你邮寄每个季度的税单、更新订阅、领薪水等容易忘记的事再好不过了。
As we ring in the New Year, let’s take stock of where we are at with the oil markets. 2014 proved to be a momentous one for the oil markets, having seen prices cut in half in just six months.
silicon

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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Total net profit for China’s commercial banks grew by 2.4 per cent last year, according to data from China’s bank regulator. Smaller banks saw increases in profit growth, while bigger banks slowed down.
Whatever happened to ‘Never complain; never explain' – the unofficial motto of the House of Windsor?

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